Patent Number: 6,310,193

Title: MurC from Streptococcus pneumoniae

Abstract: The invention provides MurC polypeptides and DNA (RNA) encoding MurC polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing MurC polypeptides to screen for antibacterial compounds.

Inventors: Black; Michael Terence (Chester Springs, PA), Hodgson; John Edward (Malvern, PA), Knowles; David Justin Charles (Boroughbridge, PA), Lonetto; Michael Arthur (Collegeville, PA), Nicholas; Richard O (Collegeville, PA), Stodola; Robert King (Flourtown, PA), Wallis; Nicola Gail (Wayne, PA)

Assignee: SmithKline Beecham Corporation

International Classification: C07K 14/195 (20060101); C07K 14/315 (20060101); C12N 9/90 (20060101); C12N 9/78 (20060101); C12N 9/12 (20060101); A61K 38/00 (20060101); A61K 39/00 (20060101); C07H 021/04 (); C12N 015/09 (); C12N 005/00 (); C12N 001/20 ()

Expiration Date: 10/30/2018