Patent Number: 6,310,200

Title: Process for selective oxidation of primary alcohols of oligosaccharides

Abstract: The invention relates to a process for the selective oxidation of primary alcohols of oligosaccharides to form the corresponding carboxylic acid derivatives of the alcohols using catalytic amounts of a di-tertiary-alkyl nitroxyl free radical, characterized in that 1,3-dibromo-5,5-dimethylhydantoin or 1,3-dichoro-5,5-dimethylbydantoin is used as oxidant and the reaction is performed in neutral to basic conditions at a pH<10. The process of the invention is useful for the production of (partially protected) oligosaccharides comprising carboxylate groups, both intermediates and end products.

Inventors: Vermaas; Dirk Jan (Oss, NL)

Assignee: Akzo Nobel N.V.

International Classification: C07H 7/00 (20060101); C08B 37/00 (20060101); C07H 3/06 (20060101); C07H 3/00 (20060101); C07H 3/04 (20060101); C07H 7/033 (20060101); C07H 3/02 (20060101); C07H 7/04 (20060101); C07H 15/04 (20060101); C07H 1/00 (20060101); C07H 15/00 (20060101); C07H 007/033 ()

Expiration Date: 10/30/2018