Patent Number: 6,310,201

Title: .beta.-lactams, methods for the preparation of taxanes, and sidechain-bearing taxanes

Abstract: Novel .beta.-lactams finding utility as intermediates in the preparation of sidechain-bearing taxes such as tall and tall derivatives. The present invention also relates to novel methods of coupling .beta.-lactams to form such sidechain-bearing taxes, and to novel sidechain-bearing taxes.

Inventors: Thottathil; John K. (Robbinsville, NJ), Trifunovich; Ivan D. (Belle Mead, NJ), Kucera; David J. (Warren, NJ), Li; Wen-Sen (Lincroft, NJ)

Assignee: Bristol-Myers Squibb Company

International Classification: C07D 205/08 (20060101); C07D 305/00 (20060101); C07D 205/00 (20060101); C07D 305/14 (20060101); C07D 205/08 (); C07D 305/14 (); C07F 007/18 ()

Expiration Date: 10/30/2018