Patent Number: 6,310,211

Title: 8-hydroxy-7-substituted quinolines as anti-viral agents

Abstract: The present invention provides for 8-hydroxy-7-substituted quinoline compounds such as formula IA ##STR1## These compounds are useful as anti-viral agents. Specifically, these compounds have anti-viral activity against the herpes virus, cytomegalovirus (CMV). Many of these compounds are also active against other herpes viruses, such as the varicella zoster virus, the Epstein-Barr virus, the herpes simplex virus and the human herpes virus type 8 (HHV-8).

Inventors: Vaillancourt; Valerie Ann (Kalamazoo, MI), Romines; Karen Rene (Paw Paw, MI), Romero; Arthur Glenn (Kalamazoo, MI), Tucker; John Alan (Kalamazoo, MI), Strohbach; Joseph Walter (Mendon, MI), Bezencon; Olivier (Kalamazoo, MI), Thaisrivongs; Suvit (Kalamazoo, MI)

Assignee: Pharmacia & Upjohn Company

International Classification: C07F 7/18 (20060101); C07F 7/00 (20060101); C07D 417/00 (20060101); C07D 417/14 (20060101); C07D 401/12 (20060101); C07D 405/06 (20060101); C07D 401/00 (20060101); C07D 417/12 (20060101); C07D 405/00 (20060101); C07D 405/12 (20060101); C07D 215/00 (20060101); C07D 215/36 (20060101); C07D 215/48 (20060101); C07D 401/12 (); C07D 215/26 (); C07D 405/06 (); C07D 417/12 ()

Expiration Date: 10/30/2018