Patent Number: 6,310,243

Title: Iodinated x-ray contrast media

Abstract: The invention provides low viscosity iodinated aryl compounds, useful as X-ray contrast agents, of formula C.sub.6 R.sub.6 wherein three non-adjacent R groups are iodine and the remaining R groups are non-ionic, hydrophilic moieties, said compound being water soluble at C. to a concentration of at least 350 mgl/ml and which in aqueous solution at C. at a concentration of 350 mgl/ml has a viscosity no greater than 13.8 mPas.

Inventors: Almen; Torsten (Falsterbo, SE), Andersson; Sven (Lomma, SE), Wistrand; Lars-Goran (Lund, SE), Golman; Klaes (Rungsted Kyst, DK), Antonsen; Oyvind (Gjesaen, NO), Fossheim; Rune (Oslo, NO), Wiggen; Unni Nordby (Rasta, NO), Wikstrom; Hakan (Groningen, NL), Klingstedt; Tomas (Lund, SE), Luenbach; Ib (Dragor, DK), Berg; Arne (Blommenholm, NO), Dugstad; Harald (Oslo, NO)

Assignee: Nycomed Imaging AS

International Classification: A61K 49/04 (20060101); C07C 33/00 (20060101); C07C 33/46 (20060101); C07C 235/00 (20060101); C07C 237/46 (20060101); C07C 33/48 (20060101); C07C 235/16 (20060101); C07C 237/00 (20060101); C07C 233/03 (); A61K 049/00 ()

Expiration Date: 10/30/2018