Patent Number: 6,310,247

Title: 7-aryl-6(Z)-heptatrienoic acid retinamides

Abstract: Novel trienoic retinoid compounds of ##STR1## with apoptotic activity useful for the prevention and treatment of cancer.

Inventors: Cheung; Adrian Wai-Hing (Glen Rock, NJ), Ferguson; Stephen B. (Clifton, NJ), Foley; Louise Helen (Clifton, NJ), Lovey; Allen John (North Caldwell, NJ)

Assignee: Hoffmann-LA Roche Inc.

International Classification: C07C 235/38 (20060101); C07C 233/00 (20060101); C07C 235/00 (20060101); C07C 233/29 (20060101); C07C 233/04 (); C07C 233/09 (); A61K 031/165 ()

Expiration Date: 10/30/2018