Patent Number: 6,333,434

Title: Preparation of trifluoromethylanilines

Abstract: The invention relates to a process for the preparation oftrifluoromethylanilines of formula (I)##STR1##whereinR.sup.1 is hydrogen, fluorine, chlorine, bromine, methyl, monochloromethyl,dichloromethyl, or formyl, andR.sup.2 is hydrogen, fluorine or chlorine,with the proviso that when R.sup.1 and R.sup.2 are both hydrogen, the aminogroup is para to the trifluoromethyl group, comprising(a) nitrating a benzotrichloride of formula (II)##STR2##wherein R.sup.1 and R.sup.2 are each as defined for formula (I), therebyforming a nitrobenzotrichloride,(b) converting the trichloromethyl group of the nitrobenzotrichloride intoa trifluoromethyl group by reaction with anhydrous hydrofluoric acid,thereby forming a nitrobenzotrifluoride, and(c) reducing the nitro groups of the nitrobenzotrifluoride to form atrifluoromethylaniline of formula (I).

Inventors: Marhold; Albrecht (Leverkusen, DE), Baumann; Kathe (Koln, DE)


International Classification: C07C 209/36 (20060101); C07C 209/00 (20060101); C07C 211/00 (20060101); C07C 211/52 (20060101); C07C 209/00 ()

Expiration Date: 12/25/2014