Patent Number: 6,342,223

Title: Immunogenic composition for group B Streptococcus

Abstract: A vaccine capable of protecting a recipient from infection caused by group B Streptococcus. The vaccine provides polysaccharide-protein moieties and contain (a) a group B Streptococcus polysaccharide conjugated to (b) a functional derivative of a group B Streptococcus C protein alpha antigen that retains the ability to elicit protective antibodies against group B Streptococcus. The vaccine may contain only one type of such polysaccharide-protein unit or may contain a mixture of more than one type of unit.

Inventors: Michel; James L. (Waban, MA), Kasper; Dennis L. (Newton Centre, MA), Ausubel; Frederick M. (Newton, MA), Madoff; Lawrence C. (Boston, MA)

Assignee: The General Hospital Corporation & Brigham and Women's Hospital

International Classification: A61K 47/48 (20060101); C07K 14/195 (20060101); C07K 14/315 (20060101); C12N 15/70 (20060101); A61K 039/09 (); C07K 014/315 ()

Expiration Date: 01/29/2019