Patent Number: 6,369,218

Title: Isomerisation of 6.beta.-fluorosteroids into the corresponding 6.alpha.-fluoro derivatives

Abstract: Described herein is the isomerisation process of 6.beta.-fluorosteroids into the corresponding pharmacologically active 6.alpha.-fluoro derivatives, comprising the reaction of 6.beta.-fluorosteroids, or 6.alpha./6.beta. isomeric mixtures, with an organic base containing a diazoimino group in a suitable organic solvent.

Inventors: Cainelli; Gianfranco (Bologna, IT), Umani-Ronchi; Achille (Bologna, IT), Contento; Michele (Bologna, IT), Sandri; Sergio (Forli', IT), Da Col; Marco (Bologna, IT)

Assignee: Farmabios S.r.L

International Classification: C07J 5/00 (20060101); C07J 71/00 (20060101); C07J 005/00 (); C07J 071/00 ()

Expiration Date: 04/09/2010