Patent Number: 6,441,027

Title: Method of regulating the female reproductive system through angiogenesis inhibitors

Abstract: A method of inhibiting angiogenesis in a female mammal to regulate fertility comprising administering to the female mammal an effective amount of an angiogenesis inhibiting compound. In addition, a method of inhibiting angiogenesis in a female mammal to treat a disease or condition of the reproductive tissue that is mediated by angiogenesis comprising administering to the female mammal an effective amount of an angiogenesis inhibiting compound. AGM-1470 is provided as such an angiogenesis inhibiting compound.

Inventors: D'Amato; Robert J. (Lexington, MA), Demore; Nancy Klauber (Durham, NC)

Assignee: Children's Medical Center Corporation

International Classification: A61K 31/336 (20060101); A61K 31/335 (20060101); A61K 031/335 ()

Expiration Date: 08/27/2019