Patent Number: 6,486,315

Title: Recrystallization processes

Abstract: Mercaptoalkanoylamino lactam acids are recrystallized by treatment with an agent that minimizes the formation of disulfides. Suitable agents are bismercaptans, phosphine or phosphite reducing agents, zinc metal powder, and sodium hydrosulfite.

Inventors: Kronenthal; David R. (Yardley, PA), Deshpande; Rajendra P. (Hillsborough, NJ), Simpson; James (Hillsborough, NJ)

Assignee: Bristol-Myers Squibb Co.

International Classification: C07D 513/00 (20060101); C07D 513/04 (20060101); C07D 223/00 (20060101); C07D 223/12 (20060101); C07D 223/02 (); C07D 281/02 (); C07D 513/02 ()

Expiration Date: 11/26/2011