Patent Number: 6,514,947

Title: Formulated nucleic acid compositions and methods of administering the same for gene therapy

Abstract: Compositions and methods for administering nucleic acid compositions in vitro to cells in culture or in vivo to an organism whereby the uptake of nucleic acids is enhanced are provided. Various compositions, including those incorporating protective, interactive, non-condensing compounds, are utilized to protect and administered nucleic acid formulation, thereby prolonging the localized bioavailability of the administered nucleic acid and enhancing expression from the nucleic acid.

Inventors: Rolland; Allain (The Woodlands, TX), Mumper; Russell J. (The Woodlands, TX)

Assignee: Valentis, Inc.

International Classification: A61K 47/38 (20060101); A61K 48/00 (20060101); A61K 47/48 (20060101); A61K 47/32 (20060101); A61K 47/10 (20060101); A01N 043/04 (); A61K 009/24 (); A61K 009/16 (); A61K 009/50 ()

Expiration Date: 02/04/2020