Patent Number: 6,569,147

Title: Systems and methods of use for delivering beneficial agents for revascularizing stenotic bypass grafts and other occluded blood vessels and for other purposes

Abstract: A system and method for opening a lumen in an occluded blood vessel, e.g., a coronary bypass graft, of a living being. The system comprises an atherectomy catheter having a working head, e.g., a rotary impacting impeller, and a debris extraction sub-system. The atherectomy catheter is located within a guide catheter. The working head is arranged to operate on, e.g., impact, the occlusive material in the occluded vessel to open a lumen therein, whereupon some debris may be produced. The debris extraction sub-system introduces an infusate liquid at a first flow rate adjacent the working head and withdraws that liquid and some blood at a second and higher flow rate, through the guide catheter to create a differential flow adjacent the working head, whereupon the debris is withdrawn in the infusate liquid and blood for collection outside the being's body. A guide wire having an inflatable balloon on its distal end may be used with the atherectomy catheter to block the flow of debris distally, while enabling distal tissues to be perfused with an oxygenating liquid.

Inventors: Evans; Douglas G. (Downingtown, PA), Nash; John E. (Chester Springs, PA)

Assignee: Kensey Nash Corporation

International Classification: A61B 17/32 (20060101); A61B 17/22 (20060101); A61D 1/00 (20060101); A61D 1/02 (20060101); A61M 31/00 (20060101); A61M 031/00 ()

Expiration Date: 05/27/2020