Patent Number: 6,617,135

Title: Multiple cytokine protein complexes

Abstract: The invention relates to protein complexes and fusion proteins including at least two different cytokine molecules. The protein complexes and fusion proteins may further include a targeting moiety such as a region of an immunoglobulin. Methods of using the protein complexes and fusion proteins are also disclosed.

Inventors: Gillies; Stephen D. (Carlisle, MA), Lo; Kin-Ming (Lexington, MA)

Assignee: EMD Lexigen Research Center Corp.

International Classification: C07K 16/30 (20060101); C07K 16/18 (20060101); C07K 16/24 (20060101); A61K 48/00 (20060101); A61K 38/00 (20060101); C12N 015/62 (); C12N 015/63 (); C07K 014/54 ()

Expiration Date: 09/09/2020