Patent Number: 6,617,311

Title: Regulation of tyrosine hydroxylase

Abstract: This invention relates to methods of regulating the effect of tyrosinehydroxylase (TH). In particular it relates to increasing the effectiveamount of TH in the central nervous systems (CNS) for the purpose ofincreasing TH-mediated dopamine production in the treatment of conditionssuch as Parkinson's disease.

Inventors: Gluckman; Peter D. (Auckland, NZ), Guan; Jian (Auckland, NZ), Alexi; Tajrena (Auckland, NZ)


International Classification: A61K 38/06 (20060101); A61K 38/05 (20060101); A61K 038/05 (); A61K 038/06 ()

Expiration Date: 09/02015