Patent Number: 6,617,317

Title: Boronic ester and acid compositions

Abstract: Disclosed herein is a method for reducing the rate of degradation of proteins in an animal comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses.

Inventors: Adams; Julian (Brookline, MA), Ma; Yu-Ting (Lexington, MA), Stein; Ross (Sudbury, MA), Baevsky; Matthew (Boston, MA), Grenier; Louis (Medford, MA), Plamondon; Louis (Watertown, MA)

Assignee: Millennium Pharmaceuticals, Inc.

International Classification: C07K 5/00 (20060101); C07F 5/02 (20060101); C07K 5/06 (20060101); C07F 5/00 (20060101); A61K 38/00 (20060101); A61K 031/69 ()

Expiration Date: 09/09/2020