Patent Number: 6,617,332

Title: Tan-1057 derivatives

Abstract: The invention relates to novel natural product derivatives of the formula(I), to processes for their preparation, to pharmaceutical compositionscomprising them and to their use in the treatment of disorders in humansor animals:##STR1##in which R.sup.1, D, X, Y and Z are defined as in claim 1.

Inventors: Brands; Michael (Wuppertal, DE), Es-Sayed; Mazen (Langenfeld, DE), Habich; Dieter (Wuppertal, DE), Raddatz; Siegfried (Koln, DE), Kruger; Joachim (Wuppertal, DE), Endermann; Rainer (Wuppertal, DE), Gahlmann; Reinhold (Wuppertal, DE), Kroll; Hein-Peter (Wuppertal, DE), Geschke; Frank-Ulrich (Wuppertal, DE), de Meijere; Armin (Gottingen, DE), Belov; Vladimir N. (Gottingen, DE), Sokolov; Victor (St. Petersburg, RU), Kozhushkov; Sergej (Gottingen, DE), Kordes; Markus (Frankenthal, DE)

Assignee:

International Classification: A61K 31/41 (20060101); A61P 31/04 (20060101); A61K 31/495 (20060101); A61P 31/00 (20060101); A61K 31/513 (20060101); A61K 31/53 (20060101); A61K 31/505 (20060101); C07D 239/00 (20060101); C07D 403/02 (20060101); C07D 239/22 (20060101); C07D 403/00 (20060101); C07D 401/02 (20060101); C07D 401/00 (20060101); C07D 239/22 (); A61K 031/513 ()

Expiration Date: 09/02015