Patent Number: 6,762,019

Title: Epoxide polymer surfaces

Abstract: Method and reagent composition for covalent attachment of target molecules, such as nucleic acids, onto the surface of a substrate. The reagent composition includes epoxide groups capable of covalently binding to the target molecule. Optionally, the composition can contain photoreactive groups for use in attaching the reagent composition to the surface. The reagent composition can be used to provide activated slides for use in preparing microarrays of nucleic acids.

Inventors: Swan; Dale G. (St. Louis Park, MN), Swanson; Melvin J. (Carver, MN)

Assignee: SurModics, Inc.

International Classification: C07C 323/42 (20060101); C07B 61/00 (20060101); C07C 323/00 (20060101); C07C 235/00 (20060101); C07C 235/84 (20060101); C07C 45/63 (20060101); C07C 45/00 (20060101); C07H 21/00 (20060101); C12Q 1/68 (20060101); C12Q 001/68 (); C12M 001/36 (); G01N 015/06 (); C07H 021/04 ()

Expiration Date: 07/13/2021