Patent Number: 6,762,021

Title: Method for diagnosis of crohn's disease

Abstract: The present invention provides a reagent for diagnosing Crohn's disease, which contains at least one member selected from the group consisting of a group of substances having a specific affinity for a protein (or a gene thereof) whose expression is potentiated in a lesion-specific manner, such as a substance having a specific affinity for PP6 regulated by IL-2 (or a gene thereof), a substance having a specific affinity for TNIK (or a gene thereof), a substance having a specific affinity for FLIP (or a gene thereof), a substance having a specific affinity for GR.alpha. (or a gene thereof) and the like. By taking note of a gene whose expression is potentiated in a lesion-specific manner, and examining the behavior thereof by the use of this diagnostic reagent, the disease can be diagnosed easily and quickly.

Inventors: Tokunaga; Katsushi (Tokyo, JP), Tsuchiya; Naoyuki (Tokyo, JP)

Assignee: Mitsubishi Pharma Corporation

International Classification: C12Q 1/68 (20060101); C12Q 1/48 (20060101); C12Q 1/37 (20060101); C12Q 1/26 (20060101); C12Q 1/42 (20060101); C12Q 001/68 (); C12P 019/34 (); C07H 021/04 (); C12N 009/02 (); C12N 009/12 ()

Expiration Date: 07/13/2021