Patent Number: 6,762,171

Title: Fatty acid CoA thioester inhibitory substance of PPAR.alpha. and PPAR.gamma.

Abstract: The invention creates a very high-novelty medicinal drug for the carbohydrate and lipid metabolism-related diseases by finding out an inhibitory substance or antagonist against PPAR .alpha. and PPAR .gamma., and relates to an application of fatty acid CoA thioester that was found out as an active inhibitory substance against peroxisome proliferator-activated receptor .alpha. and .gamma. (hereinafter referred to as PPARs) to the assay of medicinal drug, and a use of fatty acid CoA thioester for medicinal drug.

Inventors: Murakami; Koji (Tochigi, JP), Ide; Tomohiro (Ibaragi, JP), Mochizuki; Toshiro (Saitama, JP), Kadowaki; Takashi (Kanagawa, JP)

Assignee: Kyorin Pharmaceutical Co, Ltd.

International Classification: A61K 31/675 (20060101); C07H 019/207 ()

Expiration Date: 07/12012