Patent Number: 6,762,176

Title: 2-aminopyridine derivatives, their use as medicines and pharmaceutical compositions containing them

Abstract: The invention concerns novel 2-aminopyridine derivatives having an activity inhibiting NO-synthase enzymes producing nitrogen monoxide NO and/or trapping reactive forms of oxygen, the methods for preparing them, pharmaceutical compositions containing them and their therapeutic uses, particularly their use as NO-synthase inhibitors and for trapping reactive forms of oxygen whether selectively or not.

Inventors: Chabrier de Lassauniere; Pierre-Etienne (Paris, FR), Auvin; Serge (Mauchamps, FR), Harnett; Jerry (Gif-sur-Yvette, FR), Pons; Dominique (Paris, FR), Ulibarri; Gerard (Fraze, FR), Bigg; Dennis (Gir-sur-Yvette, FR)

Assignee: Societe de Consells de Recherches et D'Applications Scientifiques (S.C.R.A.S.)

International Classification: C07D 213/00 (20060101); C07D 405/12 (20060101); C07D 405/00 (20060101); C07D 213/73 (20060101); C07D 401/04 (20060101); C07D 401/00 (20060101); A61K 031/33 (); A61K 031/44 (); C07D 213/73 (); C07D 213/00 ()

Expiration Date: 07/12012