Patent Number: 6,967,003

Title: Artificial lung of membrane type

Abstract: A membrane artificial lung performs gas exchange between blood and a gas via the membrane by flowing the blood in one side of the membrane and flowing oxygen or an oxygen-containing gas in the other side of the membrane. The membrane has a hollow fiber membrane of poly-4-methylpentene-1 and an oxygen permeation rate Q(O.sub.2) at 25.degree. C. of from 1.times.10.sup.-6 to 3.times.10.sup.-3 (cm.sup.3 (STP)/cm.sup.2.multidot.sec.multidot.cmHg) and an ethanol flux of from 0.1 to 100 ml/min.multidot.m.sup.2. The membrane has, in the side of the blood flow, a surface having an ionic complex derived from: quaternary aliphatic alkylammonium salts; and heparin or a heparin derivative. The quaternary alkylammonium salts are a quaternary aliphatic alkylammonium salt having from 22 to 26 carbon atoms in total and a quaternary aliphatic alkylammonium salt having from 37 to 40 carbon atoms in total.

Inventors: Takehisa; Toru (Chiba, JP), Sakai; Kazunari (Chiba, JP), Kashiwabara; Susumu (Shiga, JP), Tanaka; Hidenori (Shiga, JP), Satoh; Masaki (Shiga, JP), Takano; Hisateru (Osaka, JP), Taenaka; Yoshiyuki (Osaka, JP), Tatsumi; Eisuke (Osaka, JP), Nishinaka; Tomohiro (Osaka, JP)

Assignee: Dainippon Ink and Chemicals, Inc.

International Classification: A61M 1/16 (20060101); A61M 1/36 (20060101); B01D 67/00 (20060101); B01D 71/26 (20060101); B01D 71/00 (20060101); B01D 69/00 (20060101); B01D 69/08 (20060101); B01D 69/02 (20060101); A61M 037/00 (); A61M 001/14 (); B01D 063/00 ()

Expiration Date: 1/22/02018