Patent Number: 6,967,082

Title: Monoclonal antibody

Abstract: The present invention relates to a monoclonal antibody suitable for monitoring the activity of systems involving protein C inhibitor, a method for preparation of the monoclonal antibody, a method for monitoring the activity of systems involving protein C inhibitor and a method for diagnosis of e.g. venous thrombosis, wherein the monoclonal antibody is utilized. The monoclonal antibody is suitable for monitoring the activity of systems involving protein C inhibitor, and it has specific affinity for both i) a complex between a serine proteinase and an inhibitor thereof, and ii) a cleaved and uncomplexed form of the inhibitor, but has substantially no specific affinity for the inhibitor in its uncleaved and uncomplexed form; or a derivative thereof having the same biological activity.

Inventors: Stenflo; Johan (Malmo, SE)

Assignee: Forskarpatent I Syd AB

International Classification: C07K 16/38 (20060101); G01N 033/55 ()

Expiration Date: 1/22/02018