Patent Number: 6,967,105

Title: Surface-modified wick for diagnostic test strip

Abstract: A wicking material is disclosed that exhibits a horizontal wicking velocity of at least about 1.0 millimeter per second when contacted with a physiological fluid such as blood, lymph or cellular interstitial fluid. This high wicking rate is achieved by means of treatment of a fibrous wicking material candidate with a low temperature gas plasma, particularly a glow discharge gas plasma formed in a gaseous blend made up predominantly of a mixture of oxygen with a saturated alkane chosen from the group consisting of methane, ethane and propane. Diagnostic test strips made with the surface-modified wicking material, and containing an immobilized reagent means for analysis of an analyte in a physiological fluid, show improved performance in terms of increased accuracy, finer precision of analyses, reduced time of analysis, a smaller fluid sample size requirement, and improved compliance with manufacturing standards resulting in lower manufacturing costs blood sugar determinations.

Inventors: Nomura; Hiroshi (Shorewood, MN), Kydd; Arthur R. (St. Paul, MN), Hanson; August R. (Rosemount, MN), Petersen; Robert J. (Minneapolis, MN)

Assignee: QuestStar Medical, Inc.

International Classification: G01N 1/30 (20060101); G01N 33/558 (20060101); G01N 021/77 ()

Expiration Date: 1/22/02018