Patent Number: 6,967,218

Title: Pravastatin pharmaceutical formulations and methods of their use

Abstract: The present invention relates to formulations comprising a therapeutically effective amount of pravastatin, or a pharmaceutically acceptable salt thereof, and methods of their use. The present formulations and methods are designed to release little or no pravastatin in the stomach but release a therapeutic amount of pravastatin in the small intestine, thereby limiting systemic exposure of the body to pravastatin and maximizing hepatic-specific absorption of the drug. The formulations and methods of the present invention are particularly useful for treating and/or preventing conditions that are benefited by decreasing levels of lipids and/or cholesterol in the body.

Inventors: Butler; Jackie (Westmeath, IR), Devane; John (Roscommon, IR), Stark; Paul (Westmeath, IR)

Assignee: Biovail Laboratories, Inc.

International Classification: A61K 9/28 (20060101); A61K 9/20 (20060101); A61K 031/21 (); A61K 031/225 ()

Expiration Date: 1/22/02018