Patent Number: 6,967,243

Title: Fatty acid desaturases and mutant sequences thereof

Abstract: Seeds, plants and oils are provided having high oleic acid; low linoleic acid; and low linoleic acid plus linolenic acid; and advantageous functional or nutritional properties. Plants are disclosed that contain a mutation in a delta-12 or delta-15 fatty acid desaturase gene. Preferred plants are rapeseed and sunflower plants. Plants carrying such mutant genes have altered fatty acid composition in seeds. In one embodiment, a plant contains a mutation in a region having the conserved motif His-Xaa-Xaa-Xaa-His, found in delta-12 and delta-15 fatty acid desaturases. A preferred motif has the sequence His-Glu-Cys-Gly-His. A preferred mutation in this motif has the amino acid sequence His-Lys-Cys-Gly-His. Nucleic acid fragments are disclosed that comprise a mutant delta-12 or delta-15 fatty acid desaturase gene sequence.

Inventors: Debonte; Lorin R. (Ft. Collins, CO), Fan; Zhegong (Colorado Springs, CO), Miao; Guo-Hua (Johnston, IA)

Assignee: Cargill, Incorporated

International Classification: C07C 53/00 (20060101); C07C 53/126 (20060101); C07C 57/00 (20060101); C07C 57/02 (20060101); C07C 57/03 (20060101); C12N 15/82 (20060101); C12N 9/02 (20060101); C07H 021/04 ()

Expiration Date: 1/22/02018