Patent Number: 7,045,133

Title: VEGF-D/VEGF-C/VEGF peptidomimetic inhibitor

Abstract: Monomeric monocyclic peptide inhibitors and dimeric bicyclic peptide inhibitors based on exposed loop fragments of a growth factor protein, such as loop 1, 2 or 3 of VEGF-D, and methods of making them are described as well as pharmaceutical compositions containing them and methods utilizing them.

Inventors: Achen; Marc G. (North Melbourne, AU), Hughes; Richard A. (North Melbourne, AU), Stacker; Steven (North Fitzroy, AU), Cendron; Angela (Campbellfield, AU)

Assignee: Ludwig Institute for Cancer Research

International Classification: A61K 38/12 (20060101); A61K 38/04 (20060101); A61K 39/00 (20060101)

Expiration Date: 5/16/02018