Patent Number: 7,045,298

Title: Method for identifying or screening agonist and antagonist to PPAR

Abstract: A method for identifying or screening an agonist for or antagonist to a peroxisome proliferator activated receptor (PPAR) which comprises allowing a test cell and a substance to be tested to coexist, and detecting a change in a ligand-dependent interaction between the PPAR and a coactivator in the test cells due to the substance to be tested by measuring the expression of a reporter gene as an index.

Inventors: Taniguchi; Tomoyasu (Toda, JP), Mizukami; Junko (Ootsu, JP)

Assignee: Tanabe Seiyaku Co., Ltd.

International Classification: G01N 33/53 (20060101); G01N 33/567 (20060101)

Expiration Date: 5/16/02018