Patent Number: 7,045,516

Title: Benzoxazole derivatives and drugs containing the same as the active ingredient

Abstract: A compound represented by the following general formula (1): ##STR00001## wherein R.sup.1 represents a halogen atom, R.sup.2 represents hydrogen atom or a lower alkyl group, and R.sup.3 represents hydrogen atom, a lower alkyl group, a lower alkoxyl group, a hydroxy lower alkyl group, a halogen atom, or a substituted or unsubstituted amino group, wherein a substituent on the amino group is selected from the group consisting of a lower alkyl group, a lower alkenyl group, a lower alkylcarbonyl group, and an amino protective group, or a salt thereof. The compound of the present invention or a salt thereof is useful as an active ingredient of medicaments for preventive and/or therapeutic treatment of conditions of irritable bowel syndrome and digestive tract functional disorder, or condition of diarrhea.

Inventors: Shiokawa; Sojiro (Yokohama, JP), Sato; Yasuo (Yokohama, JP), Izumi; Masaaki (Yokohama, JP), Yoshida; Satoshi (Yokohama, JP), Ito; Tomoko (Yokohama, JP), Niisato; Tetsutaro (Yokohama, JP), Murakami; Hiroshi (Kawasaki, JP)

Assignee: Koichi Shudo

International Classification: A61P 1/00 (20060101); A61K 31/55 (20060101); C07D 243/08 (20060101)

Expiration Date: 5/16/02018