Patent Number: 7,078,584

Title: Salmonella typhimurium-infected Caenorhabditis elegans for identifying inhibitors of infection

Abstract: Disclosed are screening methods for identifying the interplay between environmental and host signals (e.g., host-dependent or host-independent signals) and physiological pathogenic pathways that control or regulate genes responsible for establishing a persistent infection, as in the colonization of the gut of the nematode.

Inventors: Ausubel; Frederick M. (Newton, MA), Aballay; Alejandro (Braintree, MA), Yorgey; Peter S. (Cambridge, MA)

Assignee: The General Hospital Corporation

International Classification: A01K 67/033 (20060101)

Expiration Date: 7/18/02018