Patent Number: 7,101,672

Title: Target-dependent reactions using structure-bridging oligonucleotides

Abstract: The present invention relates to methods and compositions for analyzing nucleic acids. In particular, the present invention provides methods and compositions for the detection and characterization of nucleic acids and sequence changes. The methods of the present invention permit the detection and/or identification of genetic polymorphism such as those associated with human disease and permit the identification of pathogens (e.g., viral and bacterial strain identification).

Inventors: Dong; Fang (Madison, WI), Lyamichev; Victor I. (Madison, WI), Prudent; James R. (Madison, WI), Fors; Lance (Madison, WI), Neri; Bruce P. (Madison, WI), Brow; Mary Ann D. (Madison, WI), Anderson; Todd A. (Madison, WI), Dahlberg; James E. (Madison, WI)

Assignee: Third Wave Technologies, Inc.

International Classification: C12Q 1/68 (20060101); C07H 21/02 (20060101); C07H 21/04 (20060101)

Expiration Date: 9/05/02018