Patent Number: 7,101,695

Title: Method of producing transglutaminase having broad substrate activity

Abstract: Embodiments of the invention generally provide methods and compositions for producing recombinant transglutaminases. The purified recombinant transglutaminases of the invention are reactive to a broad range of compounds and exhibit broad substrate activity. In one embodiment, Streptoverticillium mobaraense (ATCC 29032), and Streptoverticillium cinnamoneum (ATCC 11874) recombinant transglutaminase fusion proteins purified from E. coli are provided to a better yield, higher purity, and activity than hitherto possible by recombinant DNA technology.

Inventors: Chou; Szu-Yi (Sunnyvale, CA)


International Classification: C12N 9/10 (20060101); C07H 21/04 (20060101); C12N 1/00 (20060101); C12N 15/00 (20060101)

Expiration Date: 9/05/02018