Patent Number: 7,101,850

Title: WISP polypeptides and nucleic acids encoding same

Abstract: Wnt-1-Induced Secreted Proteins (WISPs) are provided, whose genes are induced at least by Wnt-1. Also provided are nucleic acid molecules encoding those polypeptides, as well as vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides, and methods for producing the polypeptides.

Inventors: Levine; Arnold J. (New York, NY), Pennica; Diane (Burlingame, CA)

Assignee: Genentech, Inc.

International Classification: A61K 38/00 (20060101)

Expiration Date: 9/05/02018