Patent Number: 7,101,960

Title: Process for removing bile salts from a patient and alkylated compositions therefor

Abstract: The invention relates to a method for reducing serum cholesterol in a patient in need thereof and alkylated and crosslinked poly(allylamine) polymers useful in the method. The alkylated and crosslinked poly(allylamine) polymers are crosslinked with epichlorohydrin and comprise at least some n-decyl substituted nitrogen atoms and at least some hexyltrimethyl ammonium substituted nitrogen atoms.

Inventors: Mandeville, III; W. Harry (Lynnfield, MA), Holmes-Farley; Stephen Randall (Arlington, MA)

Assignee: Genzyme Corporation

International Classification: A01N 33/18 (20060101); C08G 63/08 (20060101)

Expiration Date: 9/05/02018