Patent Number: 7,102,059

Title: DNA molecules and polypeptides of Pseudomonas syringae Hrp pathogenicity island and their uses

Abstract: One aspect of the present invention relates to isolated nucleic acid molecules (i) encoding proteins or polypeptides of Pseudomonas CEL and EEL genomic regions, (ii) nucleic acid molecules which hybridize thereto under stringent conditions, or (iii) nucleic acid molecules that include a nucleotide sequence which is complementary to the nucleic acid molecules of (i) and (ii). Expression vectors, host cells, and transgenic plants which include the DNA molecules of the present invention are also disclosed. Another aspect relates to the isolated proteins or polypeptides and compositions containing the same. The nucleic acid molecules and proteins of the present invention can be used to imparting disease resistance to a plant, making a plant hypersusceptible to colonization by nonpathogenic bacteria, causing eukaryotic cell death, and treating cancerous conditions.

Inventors: Collmer; Alan (Ithaca, NY), Alfano; James R. (Lincoln, NE), Charkowski; Amy O. (Madison, WI)

Assignee: Cornell Research Foundation, Inc.

International Classification: A01H 5/00 (20060101); C07H 21/04 (20060101); C12N 15/63 (20060101); C12N 15/82 (20060101); C12N 5/14 (20060101); C12P 21/02 (20060101)

Expiration Date: 9/05/02018