Patent Number: 7,132,101

Title: Compositions and methods for eliciting an immune response to gram-negative bacterial infections

Abstract: Compositions for eliciting an immune response against Gram-negative bacterial infections and methods of making such compositions are provided. The composition comprises glycosylated pilin, the pilin being glycosylated with the O-antigen of a target Gram-negative bacteria of interest. Methods of eliciting an immune response by administration of such compositions are also provided.

Inventors: Castric; Peter A. (Pittsburgh, PA)

Assignee: Duquesne University of the Holy Ghost

International Classification: A61K 39/00 (20060101); A61K 39/02 (20060101); A61K 39/38 (20060101)

Expiration Date: 2019-11-07 0:00:00