Patent Number: 7,132,240

Title: Use of methylated nucleic acid segments for isolating centromere DNA

Abstract: The invention provides efficient methods for the isolation of centromeres from potentially any organism. Using the methods of the invention, methylated centromere DNA may be isolated from potentially any centromere in an organism. The technique is amenable to mass screenings employing use of arrays comprising libraries of DNA from a target species.

Inventors: Luo; Song (Chicago, IL), Copenhaver; Gregory (Oak Park, IL), Keith; Kevin (Chicago, IL), Preuss; Daphne (Chicago, IL)

Assignee: The University of Chicago

International Classification: C12Q 1/68 (20060101); C12P 19/34 (20060101)

Expiration Date: 2019-11-07 0:00:00