Patent Number: 7,132,427

Title: Quinazolines and uses thereof

Abstract: This invention relates to compounds of the general formula: ##STR00001## in which R.sup.A, R.sup.B, R.sup.C and R.sup.D are as defined herein, and to their preparation and use.

Inventors: Wang; Yihan (Newton, MA), Metcalf, III; Chester A. (Needham, MA), Shakespeare; William C. (Southborough, MA), Sawyer; Tomi K. (Southborough, MA), Bohacek; Regine (Boston, MA), Sundaramoorthi; Rajeswari (Watertown, MA)

Assignee: Ariad Pharmaceuticals, Inc.

International Classification: A61K 31/70 (20060101); A61K 31/517 (20060101); C07D 401/00 (20060101); C07D 403/00 (20060101); C07D 413/00 (20060101); C07D 417/00 (20060101); C07D 419/00 (20060101); C07F 9/02 (20060101); A01N 43/04 (20060101); A61P 19/10 (20060101); C07H 11/04 (20060101); C08B 3/00 (20060101)

Expiration Date: 2019-11-07 0:00:00