Patent Number: 7,132,449

Title: Inhibitors of cruzipain and other cysteine proteases

Abstract: Compounds of general formula (I): ##STR00001## wherein R.sup.1, R.sup.2, Y, (X).sub.o, (W).sub.n, (V).sub.m, Z and U are as defined in the specification, are inhibitors of cruzipain and other cysteine protease inhibitors and are useful as therapeutic agents, for example in Chagas' disease, or for validating therapeutic target compounds.

Inventors: Quibell; Martin (Cambridge, GB)

Assignee: Amura Therapeutics Limited

International Classification: A61K 31/34 (20060101); C07D 307/02 (20060101)

Expiration Date: 2019-11-07 0:00:00