Patent Number: 7,132,544

Title: Process for the preparation of tetrasubstituted imidazole derivatives and novel crystalline structures thereof

Abstract: The present invention relates to a process for preparing tetrasubstituted imidazole derivatives of the general formula (I) ##STR00001## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are as defined in the specification below. The present invention further relates to a process for preparing the compound of formula (II) ##STR00002## and novel crystalline structures of the compound of formula (II).

Inventors: Zhong; Hua (Lansdale, PA), Dubberke; Silke (Floershein, DE), Muller; Stefan (Zurich, CH), Rossler; Armin (Schaffhausen, CH), Schultz; Thomas W. (Richboro, PA), Korey; Daniel J. (Yardley, PA), Otten; Thomas (Zurich, CH), Walker; Donald G. (Pipersville, PA), Abdel-Magid; Ahmed (Ambler, PA)

Assignee: Ortho-McNeil Pharmaceutical, Inc.

International Classification: C07D 401/04 (20060101); C07D 233/64 (20060101)

Expiration Date: 2019-11-07 0:00:00