Patent Number: 7,132,545

Title: Synthesis of nicotine derivatives from nicotine

Abstract: Methods of synthesizing nicotine analogs and derivatives are described. In some embodiments the methods utilize an alkyl or aryl silyl-substituted nicotine analog intermediate. Intermediates useful for the synthesis of nicotine and nicotine analogs are also described.

Inventors: Comins; Daniel L. (Cary, NC), Smith; Emilie Despagnet (Raleigh, NC)

Assignee: North Carolina State University

International Classification: C07D 401/04 (20060101); C07D 401/02 (20060101)

Expiration Date: 2019-11-07 0:00:00