Patent Number: 7,132,560

Title: Crystal of bicalutamide and production method thereof

Abstract: The present invention relates to a crystal of bicalutamide having a defined form, as well as economical and industrially practical production methods of bicalutamide and a crystal thereof, which are superior in environmental benignity and safety. Accordingly, the present invention provides a production method of bicalutamide represented by the formula (I): ##STR00001## which includes at least a step of reacting a compound represented by the formula (3): ##STR00002## with an oxidizing agent, a production method of a crystal of bicalutamide, as well as a crystal form of bicalutamide as defined by X-ray diffraction (XRD) or solid .sup.13C NMR measurement.

Inventors: Shintaku; Tetsuya (Osaka, JP), Katsura; Tadashi (Osaka, JP), Itaya; Nobushige (Osaka, JP)

Assignee: Sumitomo Chemical Company, Limited

International Classification: C07C 255/00 (20060101)

Expiration Date: 2019-11-07 0:00:00