Patent Number: 7,132,570

Title: Method for the production of crystalline forms and crystalline forms of optical enantiomers of modafinil

Abstract: The invention relates to a process for the preparation of crystalline forms of the optical enantiomers of modafinil, comprising stages comprising: i) dissolving one of the optical enantiomers of modafinil in a solvent other than ethanol, ii) crystallising the modafinil enantiomer, iii) recovering the crystalline form of the modafinil enantiomer so obtained. The invention also relates to a process for the preparation of the optical enantiomers of modafinil.

Inventors: Neckebrock; Olivier (Ponteau Combault, FR), Leproust; Pierre (Creteil, FR)

Assignee: Cephalon France

International Classification: C07C 233/05 (20060101); A61K 31/165 (20060101)

Expiration Date: 2019-11-07 0:00:00