Patent Number: 7,611,721

Title: Adjuvant combination formulations

Abstract: The use of 3-O-deacylated monophosphoryl lipid A or monophosphoryl lipid A and derivatives and analogs thereof, in combination with a cytokine or lymphokine such as granulocyte macrophage colony stimulating factor or interleukin-12 is useful as an adjuvant combination in an antigenic composition to enhance the immune response in a vertebrate host to a selected antigen.

Inventors: Hagen; Michael (Pittsford, NY)

Assignee: Wyeth Holdings Corporation

International Classification: A61K 47/00 (20060101)

Expiration Date: 1/03/02017