Patent Number: 7,611,729

Title: Dosage forms having prolonged active ingredient release

Abstract: The present invention relates to prolonged-release oral dosage forms of 4-phenylbutyric acid salts, such as sodium 4-phenylbutyrate. The prolonged release oral dosage forms are preferably tablets. The prolonged release is achieved by formulating 4-phenylbutyric acid with a delaying matrix material, such as hydroxypropylmethyl cellulose. The prolonged release oral dosage forms of the present invention may be administered once or twice a day to a patient suffering from a disease such as cancer or a urea cycle disorder.

Inventors: Truog; Peter (Basel, CH)

Assignee: Lunamed AG

International Classification: A61K 9/22 (20060101); A01N 61/00 (20060101); A61K 31/00 (20060101)

Expiration Date: 1/03/02017