Patent Number: 7,611,731

Title: Mesostructured silica/block copolymer monoliths as a controlled release device and methods of manufacture

Abstract: The invention comprises the design, synthesis, and characterization of mesostructured silica/block copolymer composite monoliths as controlled release systems. The controlled release function is based on the formation of mesostructured silica/block copolymer architectures via surfactant-templated sol-gel processing. Multi-layered or gradient monoliths are produced by layer-by-layer sol-gel processing to provide pulsed and programmed release characteristics. A simple, rapid route to prepare combinatorial compositional monolith libraries provides high-throughput synthesis and rapid screening of the release characteristics of the monoliths.

Inventors: Wyrsta; Michael D. (Santa Barbara, CA), Phillips; Mark L. F. (Hayward, CA)

Assignee: SBA Materials, Inc.

International Classification: A61K 9/14 (20060101); A61B 5/055 (20060101); A61K 9/16 (20060101)

Expiration Date: 1/03/02017