Patent Number: 7,611,865

Title: Polynucleotides encoding truncated glial cell line-derived neurotrophic factor

Abstract: Disclosed are novel proteins, referred to as truncated glial cell line-derived neurotrophic factor (truncated GDNF) proteins, that promote dopamine uptake by dopaminergic cells and promote the survival of nerve cells. Also disclosed are processes for obtaining the truncated GDNF proteins by recombinant genetic engineering techniques.

Inventors: Hu; Shaw-Fen Sylvia (Thousand Oaks, CA)

Assignee: Amgen Inc.

International Classification: C12P 21/06 (20060101); C07H 21/02 (20060101); C07H 21/04 (20060101); C12N 15/63 (20060101); C12N 5/10 (20060101)

Expiration Date: 1/03/02017