Patent Number: 7,611,876

Title: PUFA polyketide synthase systems and uses thereof

Abstract: The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.

Inventors: Metz; James G. (Longmont, CO), Weaver; Craig A. (Boulder, CO), Barclay; William R. (Boulder, CO), Flatt; James H. (Colorado Springs, CO)

Assignee: Martek Biosciences Corporation

International Classification: C12N 15/52 (20060101); C12N 15/53 (20060101); C12N 15/74 (20060101); C12N 15/79 (20060101); C12N 15/82 (20060101); C12P 7/64 (20060101)

Expiration Date: 1/03/02017