Patent Number: 7,611,902

Title: Diagnostic method for myopathy

Abstract: This invention provides a diagnostic method for determining statin induced myopathy. The method is especially applicable for determining warnings, early signs and also symptomatic myopathy. The method includes collecting a lipidomic profile from a biological sample such as blood or serum and comparing the obtained lipidomic profile to reference lipidomic markers. The reference lipidomic markers have been established by combining a pro-inflammatory muscle tissue gene expression profile with a lipidomic profile associated with high dosage statin treatment. This invention also relates to a kit for performing a method for determining statin induced myopathy.

Inventors: Laaksonen; Reijo (Lempaala, FI), Oresic; Matej (Espoo, FI), Lehtimaki; Terho (Tampere, FI), Paiva; Hannu (Tampere, FI)

Assignee: Zora Biosciences Oy

International Classification: G01N 33/48 (20060101); G01N 33/92 (20060101)

Expiration Date: 1/03/02017