Patent Number: 7,612,090

Title: Aryl and heteroaryl substituted tetrahydroisoquinolines and use thereof

Abstract: Provided herein are compounds of the formula (I): ##STR00001## wherein R.sup.1-R.sup.8 are as described herein, R.sup.4 being aryl or heteroaryl Such compounds are particularly useful in the treatment of a disorder which is created by or is dependent upon decreased availability of serotonin, norepinephrine or dopamine.

Inventors: Beck; James P. (Kalamazoo, MI), Curry; Matt A. (Coatesville, PA), Smith; Mark A. (Landenberg, PA)

Assignee: Albany Molecular Research, Inc.

International Classification: C07D 217/00 (20060101); A61K 31/47 (20060101)

Expiration Date: 1/03/02017